Publication

† These authors contributed equally to this work.

* Corresponding author

<2025>

30. Minjae Kim†, Jinwoo Kim†, Gyu Sung Lee, Paul Dominic B. Olinares, Yougant Airan, Jasmine L. Chow, Jongseok Park, Yujin Jeong, Jiho Park, Brian T. Chait, Seth B. Herzon, Chung Sub Kim*, Jin Young Kang*. "Structural study on human microbiome-derived polyketide synthases that assemble genotoxic colibactin." Structure, 33, 1–16 (2025. 05. 16) [Link]

29. Haerang Hwang, Bum-Joon Jung, Jiho Park, Yujin Jeong, Yo-han Choi, Jin Young Kang*, Wonhee Lee*. "Integrated Parylene-Based Thin-Film Microfluidic Device for Time-Resolved Cryo-Electron Microscopy." Advanced Functional Materials, 2418224 (2025. 01. 28) [Link]

28. Hyeok Jin Oh, Yongsuk Lee, Haerang Hwang, Kibeom Hong, Hyeongjoo Choi, Jin Young Kang, Yongwon Jung*. "Size-controlled assembly of phase separated protein condensates with interfacial protein cages." Nature Communications, 16, 1006 (2025. 01. 25) [Link]

<2024>

27. JH Cha, S-H Lee, Y Yun, WH Choi, H Koo, SH Jung, HB Chae, DH Lee, SJ Lee, DH Jo, JH Kim, JJ Song, J-H Chae, JH Lee, J Park, JY Kang, S Bae*, and S-Y Lee*. “Discovery of novel disease-causing mutation in SSBP1 and its correction using adenine base editor to improve mitochondrial function.” Molecular Therapy Nucleic Acids, 35(3), 102257 (2024. 09. 10). [Link]

26. Jinwoo Kim and Jin Young Kang*. "Practices in cryo-EM single particle analysis data processing: data transfer between RELION and cryoSPARC." BioDesign, 12(2): 29-38 (2024. 06. 30). [Link]

<2023>

25. Gunhyoung Lim, Seungha Hwang, Kilwon Yu, Jin Young Kang, Changwon Kang*, and Sungchul Hohng*. "Translocating RNA polymerase generates R-loops at DNA double-strand breaks without any additional factors." Nucleic Acid Research, gkad689 (2023. 10. 13). [Link]

24. Seungha Hwang and Jin Young Kang*. "To burst or hide." Structure, 31, 893-894 (2023. 08. 03). (Preview) [Link]

23. Eunho Song, Seungha Hwang, Palinda Ruvan Munasingha, Yeon-Soo Seo, Jin Young Kang*, Changwon Kang*, and Sungchul Hohng*. "Transcriptional pause extension benefits the stand-by rather than catch-up Rho-dependent termination." Nucleic Acid Research, 51(6), 2778-2789 (2023. 04. 11). [Link]

22. Jin Young Kang†, Tatiana V. Mishanina†, Yu Bao†, James Chen, Eliza Llewellyn, James Liu, Seth A. Darst*, and Robert Landick*. "An ensemble of interconnecting conformations of the elemental paused transcription complex creates regulatory options." PNAS, 120(8), e2215945120 (2023. 01. 10). [Link]

<2022>

21. Songwon Kim, Sang Soo Lee, Jun Gyou Park, Ji Won Kim, Seulgi Ju, Seung Hun Choi, Subin Kim, Na Jin Kim, Semi Hong, Jin Young Kang*, and Mi Sun Jin*. "Structural Insights into Porphyrin Recognition by the Human ATP-binding cassette transporter ABCB6." Molecules and Cells, 45(8), 575-587 (2022. 08. 31). [Link]

20. Seungha Hwang, Paul Dominic B. Olinares, Jimin Lee, Jinwoo Kim, Brian T. Chait, Rodney A. King, and Jin Young Kang*. "Structural basis of transcriptional regulation by a nascent RNA element, HK022 putRNA." Nature Communications, 13, 4668 (2022. 08. 15). [Link]

19. Yeolin Lee, Minjae Kim, Jin Young Kang, and Yongwon Jung*. “Protein cages engineered for interaction-driven selective encapsulation of biomolecules.” Applied Materials & Interfaces, 14, 31, 35357-35365 (2022. 08. 02). [Link]

18. Eunho Song, Heesoo Uhm, Palinda Ruvan Munasingha, Seungha Hwang, Yeon-Soo Seo, Jin Young Kang*, Changwon Kang*, and Sungchul Hohng*. “Rho-dependent transcription termination proceeds via three routes.” Nature Communications, 13, 1663 (2022. 03. 29). [Link]

<2021>

17. Juhyun Lee, Si-Eun Sung, Janghyun Lee, Jin Young Kang*, Joon-Hwa Lee*, and Byong-Seok Choi*. “Base-pair opening dynamics study of fluoride riboswitch in the Bacillus cereus CrcB gene.” International Journal of Molecular Sciences, 22, 3234-3245 (2021. 03. 22). [Link]

16. Wooyoung Kang, Seungha Hwang, Jin Young Kang, Changwon Kang*, and Sungchul Hohng*. “Hopping and flipping of RNA polymerase on DNA during recycling for reinitiation after intrinsic termination in bacterial transcription.” International Journal of Molecular Sciences, 22(5):2398-2410 (2021. 02. 27). [Link]

15. Paul Dominic B. Olinares, Jin Young Kang, Eliza Llewellyn, Courtney Chiu, James Chen, Brandon Malone, Ruth M. Saecker, Elizabeth A. Campbell, Seth A. Darst, and Brian T. Chait*. “Native mass spectrometry-based screening for optimal sample preparation in Single-Particle Cryo-EM.” Structure, 29(2), 186-195 (2021. 02. 04). [Link]

14. Jin Young Kang†, Eliza Llewellyn†, James Chen, Paul Dominic B. Olinares, Joshua Brewer, Brian T. Chait, Elizabeth A. Campbell, and Seth A. Darst*. “Structural basis for transcription complex disruption by the Mfd translocase.” eLife, 10:e62117 (2021. 01. 22). [Link]

<2020>

13. Seungha Hwang†, Jimin Lee† and Jin Young Kang*. "Prokaryotic transcription regulation by the nascent RNA elements." BioDesign, 8(2): 33-40 (2020. 06. 09). [Link]

12. Ki-Hun Kim, Jihyun Hwang, Jin Hong Kim, Kyung-Pyo Son, Yejin Jang, Mihyein Kim, Suk-Jo Kang, Jie-Oh Lee, Jin Young Kang*, and Byong-Seok Choi*. “Structural and biophysical properties of RIG-I bound to dsRNA with G-U wobble base pairs.” RNA Biology, 17(3):325-334 (2020. 03. 17). [Link]

<2019>

11. Jin Young Kang*, Tatiana V. Mishanina*, Robert Landick and Seth A. Darst*. “Mechanisms of transcriptional pausing in bacteria.” Journal of Molecular Biology, 431:4007-4029 (2019. 09. 20). [Link]

10. Byungchul Kim, Yen-Chih Wang, Charles W. Hespen, Juliel Espinosa, Jeanne Salje, Kavita J. Rangan, Deena A. Oren, Jin Young Kang, Virginia A. Pedicord and Howard C. Hang*. “Enterococcus faecium secreted antigen A generates muropeptides to enhance host immunity and limit bacterial pathogenesis.” eLife 8:e453436 (2019. 04. 10). [Link]

9. James Chen, Alex J. Noble, Jin Young Kang and Seth A. Darst, “Eliminating effects of particle adsorption to the air/water interface in single-particle cryo-electron microscopy: Bacterial RNA polymerase and CHAPSO.”, Journal of Structural Biology:X, https://doi.org/10.1016/j.yjsbx.2019.100005 (2019. 02. 14). [Link]

8. JY Kang, RA Mooney, Y Nediakov, J Saba, TV Mishanina, I Artsimovitch, R Landick and SA Darst*. “Structural basis for transcript elongation control by NusG/RfaH universal regulators.”, Cell 173, 1650–1662 (2018. 06. 14). [Link]

7. JY Kang, TV Mishanina, MJ Bellecourt, RA Mooney, SA Darst* and R Landick*. “RNA polymerase accommodates a pause RNA hairpin by global conformational rearrangements that prolong pausing.” Mol. Cell 69, 802-815 (2018. 03. 01). [Link]

6. JY Kang, PDB Olinares, J Chen, EA Campbell, A Mustaev, BT Chait, ME Gottesman, and SA Darst*. “Structural basis of transcription arrest by coliphage HK022 Nun in an Escherichia coli RNA polymerase elongation complex.” eLife 6, e25478 (2017. 03. 20). [F1000 Prime Recommended: F1000Prime.com/727423159] [Link]

5. JY Kang and J,-O Lee*. “Structural Biology of the Toll-Like Receptor Family.” Annu. Rev. Biochem. 80, 917-941 (2011. 05. 05). [Link]

4. JY Kang†, X Nan†, MS Jin, S,-J Youn, YH Ryu, S Mah, SH Han, H Lee, S,-G Paik*, and J,-O Lee*. “Recognition of Lipopeptide Patterns by Toll-like Receptor 2-Toll-like Receptor 6 Heterodimer.” Immunity 31, 873-884 (2009. 12. 18). [Link]

3. MS Jin, SE Kim†, JY Heo†, ME Lee, HM Kim, S,-G Paik, H Lee, and J,-O Lee*. “Crystal Structure of TLR1-TLR2 Heterodimer Induced by Binding of a Tri-Acylated Lipopeptide.” Cell 130, 1071-1082 (2007. 09. 21). [F1000 Prime Recommended: F1000Prime.com/1091080] [Link]

2. HM Kim, SC Oh, KJ Lim, J Kasamatsu, JY Heo, BS Park, H Lee, OJ Yoo, M Kasahara, and J,-O Lee*. “Structural Diversity of the Hagfish Variable Lymphocyte Receptors.” J. Biol. Chem. 282(9), 6726-6732, (2007. 03. 02). [Link]

1. DJ Kim, JY Heo, KS Kim, and IS Choi*. “Formation of Thermoresponsive Poly(N-isopropylacrylamide)/Dextran Particles by Atom Transfer Radical Polymerization.” Macromol. Rapid commun. 24(8), 517-521 (2003. 05. 19). [Link]