Publication

† These authors contributed equally to this work.

* Corresponding author

<2024>

27. JH Cha, S-H Lee, Y Yun, WH Choi, H Koo, SH Jung, HB Chae, DH Lee, SJ Lee, DH Jo, JH Kim, JJ Song, J-H Chae, JH Lee, J Park, JY Kang, S Bae*, and S-Y Lee*. “Discovery of novel disease-causing mutation in SSBP1 and its correction using adenine base editor to improve mitochondrial function.” Molecular Therapy Nucleic Acids, 35(3), 102257 (2024). [Link]

26. Jinwoo Kim and Jin Young Kang*. "Practices in cryo-EM single particle analysis data processing: data transfer between RELION and cryoSPARC." BioDesign, 12(2): 29-38 (2024). [Link]

<2023>

25. Gunhyoung Lim, Seungha Hwang, Kilwon Yu, Jin Young Kang, Changwon Kang*, and Sungchul Hohng*. "Translocating RNA polymerase generates R-loops at DNA double-strand breaks without any additional factors." Nucleic Acid Research, gkad689 (2023). [Link]

24. Seungha Hwang and Jin Young Kang*. "To burst or hide." Structure, 31, 893-894 (2023). (Preview) [Link]

23. Jin Young Kang†, Tatiana V. Mishanina†, Yu Bao†, James Chen, Eliza Llewellyn, James Liu, Seth A. Darst*, and Robert Landick*. "An ensemble of interconnecting conformations of the elemental paused transcription complex creates regulatory options." PNAS, 120(8), e2215945120 (2023). [Link]

22. Eunho Song, Seungha Hwang, Palinda Ruvan Munasingha, Yeon-Soo Seo, Jin Young Kang*, Changwon Kang*, and Sungchul Hohng*. "Transcriptional pause extension benefits the stand-by rather than catch-up Rho-dependent termination." Nucleic Acid Research, 51(6), 2778-2789 (2023). [Link]

<2022>

21. Songwon Kim, Sang Soo Lee, Jun Gyou Park, Ji Won Kim, Seulgi Ju, Seung Hun Choi, Subin Kim, Na Jin Kim, Semi Hong, Jin Young Kang*, and Mi Sun Jin*. "Structural Insights into Porphyrin Recognition by the Human ATP-binding cassette transporter ABCB6." Molecules and Cells, 45(8), 575-587 (2022). [Link]

20. Seungha Hwang, Paul Dominic B. Olinares, Jimin Lee, Jinwoo Kim, Brian T. Chait, Rodney A. King, and Jin Young Kang*. "Structural basis of transcriptional regulation by a nascent RNA element, HK022 putRNA." Nature Communications, 13, 4668 (2022). [Link]

19. Yeolin Lee, Minjae Kim, Jin Young Kang, and Yongwon Jung*. “Protein cages engineered for interaction-driven selective encapsulation of biomolecules.” Applied Materials & Interfaces, 14, 31, 35357-35365 (2022). [Link]

18. Eunho Song, Heesoo Uhm, Palinda Ruvan Munasingha, Seungha Hwang, Yeon-Soo Seo, Jin Young Kang*, Changwon Kang*, and Sungchul Hohng*. “Rho-dependent transcription termination proceeds via three routes.” Nature Communications, 13, 1663 (2022). [Link]

<2021>

17. Juhyun Lee, Si-Eun Sung, Janghyun Lee, Jin Young Kang*, Joon-Hwa Lee*, and Byong-Seok Choi*. “Base-pair opening dynamics study of fluoride riboswitch in the Bacillus cereus CrcB gene.” International Journal of Molecular Sciences, 22, 3234-3245 (2021). [Link]

16. Wooyoung Kang, Seungha Hwang, Jin Young Kang, Changwon Kang*, and Sungchul Hohng*. “Hopping and flipping of RNA polymerase on DNA during recycling for reinitiation after intrinsic termination in bacterial transcription.” International Journal of Molecular Sciences, 22(5):2398-2410 (2021). [Link]

15. Jin Young Kang†, Eliza Llewellyn†, James Chen, Paul Dominic B. Olinares, Joshua Brewer, Brian T. Chait, Elizabeth A. Campbell, and Seth A. Darst*. “Structural basis for transcription complex disruption by the Mfd translocase.” eLife, 10:e62117 (2021). [Link]

14. Paul Dominic B. Olinares, Jin Young Kang, Eliza Llewellyn, Courtney Chiu, James Chen, Brandon Malone, Ruth M. Saecker, Elizabeth A. Campbell, Seth A. Darst, and Brian T. Chait*. “Native mass spectrometry-based screening for optimal sample preparation in Single-Particle Cryo-EM.” Structure, 29(2), 186-195 (2021). [Link]

<2020>

13. Seungha Hwang†, Jimin Lee† and Jin Young Kang*. "Prokaryotic transcription regulation by the nascent RNA elements." BioDesign, 8(2): 33-40 (2020). [Link]

12. Ki-Hun Kim, Jihyun Hwang, Jin Hong Kim, Kyung-Pyo Son, Yejin Jang, Mihyein Kim, Suk-Jo Kang, Jie-Oh Lee, Jin Young Kang*, and Byong-Seok Choi*. “Structural and biophysical properties of RIG-I bound to dsRNA with G-U wobble base pairs.” RNA Biology, 17(3):325-334 (2020). [Link]

<2019>

11. Jin Young Kang*, Tatiana V. Mishanina*, Robert Landick and Seth A. Darst*. “Mechanisms of transcriptional pausing in bacteria.” Journal of Molecular Biology, 431:4007-4029 (2019). [Link]

10. Byungchul Kim, Yen-Chih Wang, Charles W. Hespen, Juliel Espinosa, Jeanne Salje, Kavita J. Rangan, Deena A. Oren, Jin Young Kang, Virginia A. Pedicord and Howard C. Hang*. “Enterococcus faecium secreted antigen A generates muropeptides to enhance host immunity and limit bacterial pathogenesis.” eLife 8:e453436 (2019). [Link]

9. James Chen, Alex J. Noble, Jin Young Kang and Seth A. Darst, “Eliminating effects of particle adsorption to the air/water interface in single-particle cryo-electron microscopy: Bacterial RNA polymerase and CHAPSO.”, Journal of Structural Biology:X, https://doi.org/10.1016/j.yjsbx.2019.100005 (2019). [Link]

8. JY Kang, RA Mooney, Y Nediakov, J Saba, TV Mishanina, I Artsimovitch, R Landick and SA Darst*. “Structural basis for transcript elongation control by NusG/RfaH universal regulators.”, Cell 173, 1650–1662 (2018). [Link]

7. JY Kang, TV Mishanina, MJ Bellecourt, RA Mooney, SA Darst* and R Landick*. “RNA polymerase accommodates a pause RNA hairpin by global conformational rearrangements that prolong pausing.” Mol. Cell 69, 802-815 (2018). [Link]

6. JY Kang, PDB Olinares, J Chen, EA Campbell, A Mustaev, BT Chait, ME Gottesman, and SA Darst*. “Structural basis of transcription arrest by coliphage HK022 Nun in an Escherichia coli RNA polymerase elongation complex.” eLife 6, e25478 (2017). [F1000 Prime Recommended: F1000Prime.com/727423159] [Link]

5. JY Kang and J,-O Lee*. “Structural Biology of the Toll-Like Receptor Family.” Annu. Rev. Biochem. 80, 917-941 (2011). [Link]

4. JY Kang†, X Nan†, MS Jin, S,-J Youn, YH Ryu, S Mah, SH Han, H Lee, S,-G Paik*, and J,-O Lee*. “Recognition of Lipopeptide Patterns by Toll-like Receptor 2-Toll-like Receptor 6 Heterodimer.” Immunity 31, 873-884 (2009). [Link]

3. MS Jin, SE Kim†, JY Heo†, ME Lee, HM Kim, S,-G Paik, H Lee, and J,-O Lee*. “Crystal Structure of TLR1-TLR2 Heterodimer Induced by Binding of a Tri-Acylated Lipopeptide.” Cell 130, 1071-1082 (2007). [F1000 Prime Recommended: F1000Prime.com/1091080] [Link]

2. HM Kim, SC Oh, KJ Lim, J Kasamatsu, JY Heo, BS Park, H Lee, OJ Yoo, M Kasahara, and J,-O Lee*. “Structural Diversity of the Hagfish Variable Lymphocyte Receptors.” J. Biol. Chem. 282(9), 6726-6732, (2007). [Link]

1. DJ Kim, JY Heo, KS Kim, and IS Choi*. “Formation of Thermoresponsive Poly(N-isopropylacrylamide)/Dextran Particles by Atom Transfer Radical Polymerization.” Macromol. Rapid commun. 24(8), 517-521 (2003). [Link]